2 capsules daily, with a meal.
Two (size 00) vegetarian capsules contain:
BioResponse DIM® diindolylmethane complex 100 mg
(complex of starch, diindolylmethane, vitamin E (tocophersolan),
phosphatidylcholine and silica) (standardized to contain 25% diindolylmethane)
Calcium-D-glucarate 100 mg
Broccoli (Brassica oleracea italica) sprout concentrate (whole 100 mg
plant) (standardized to contain a minimum of 400 mcg sulforaphane)
HMRlignan™ (from Norway spruce knot wood) 10 mg
(containing 7-hydroxymatairesinol)
Alpha lipoic acid (thioctic acid) 200 mg
N-Acetyl-l-cysteine (free-form) 200 mg
Milk thistle (Silybum marianum) extract (seed) 150 mg
(standardized to contain 80% silymarin)
l-Methionine (free-form) 200 mg
Glycine (free-form) 100 mg
Taurine (free-form) 100 mg
Other ingredients: vegetarian capsule (cellulose, water), hypoallergenic
plant fiber (cellulose), ascorbyl palmitate
HMRlignan™ is a trademark of Linnea Inc. BioResponse DIM® and DIMPRO® are trademarks of BioResponse, L.L.C., Boulder, CO. This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, Inc. and protected by U.S. Patent 7,662,863.​

GF, Non GMO, V, Veg

DIM Detox

Pure Encapsulations

60 caps


The glucosinolates in broccoli, including indole-3-carbinol and sulforaphane, help support healthy detoxification. BioResponse
DIM® provides 25 mg per serving of a highly absorbable form of diindolylmethane, an important metabolite of indole-3-carbinol.
These compounds promote healthy estrogen metabolism and cell cycle activity. Calcium-D-glucarate targets beta-glucuronidase
enzyme activity, promoting healthy hormone detoxification through the glucuronidation pathway. Lignans, such as 7-ydroxymatairesinol (HMR), are converted in the body to enterolactone. Research indicates that dietary intake of lignans and healthy serum enterolactone levels provide support for cellular, heart, breast, bone and cognitive health. Silymarin, alpha lipoic acid and n-acetyl-l-cysteine act to support phase II detoxification enzyme activity in the liver and offer antioxidant support for cellular protection. Taurine, glycine and methionine promote phase II detoxification pathways and healthy cell metabolism.‡

Dr. W's Comments:

This is a great detox support! It is especially useful for menstrual issues where estrogen balance is the problem because of both the Dim component and the calcium-d-glucarate. It also has an especially good assortment of Phase 2 detoxifiers – amino acids like glycine, taurine, methionine, cysteine; sulfate conjugation via the broccoli sprout concentrate. Add the milk thistle extract, lipoic acid and other components and you have one of the best for a single detox support.